Absolute Eosinophil Count Calculator

Calculate the absolute eosinophil count from complete blood count results

Calculate Absolute Eosinophil Count

cells/μL

Normal range: 4,000-11,000 cells/μL

%

Normal range: 1-4% of total WBC count

Formula:

AEC = WBC × EOS%

Example Calculation

Given: WBC = 9,000 cells/μL, Eosinophils = 5%

Calculation: AEC = 9,000 × 0.05 = 450 cells/μL = 0.45 × 10³ cells/μL

Interpretation: Upper limit of normal range

Common Clinical Conditions

Eosinophilia Causes

Allergic Conditions:

  • • Bronchial asthma
  • • Atopic dermatitis
  • • Allergic rhinitis
  • • Food allergies

Infections:

  • • Parasitic infections
  • • Helminthic infestations
  • • Fungal infections

Medications:

  • • Antibiotics
  • • Anticonvulsants
  • • Sulfonamides

Other Causes:

  • • Autoimmune disorders
  • • Malignancies
  • • Hypereosinophilic syndrome

Eosinopenia Causes

• Acute bacterial infections

• Corticosteroid therapy

• Severe stress or burns

• Cushing's syndrome

• Alcohol abuse

Reference Ranges

Normal Range

0.04 - 0.45 × 10³ cells/μL

1-4% of total WBC

Eosinophilia

> 0.45 × 10³ cells/μL

May indicate allergies

Hypereosinophilia

> 1.5 × 10³ cells/μL

Requires investigation

About Eosinophils

Function

White blood cells specialized in fighting parasites and mediating allergic responses

Origin

Named "acidophils" due to their affinity for acidic dyes like eosin

Clinical Significance

Used as markers for asthma severity and allergic disease monitoring

Units Conversion

× 10³ cells/μL= × 10⁹ cells/L
cells/μL= cells per microliter
Note: Both unit expressions (× 10³ cells/μL and × 10⁹/L) are equivalent and commonly used in clinical laboratories.

When to Test AEC

Suspected Allergies

  • • Asthma evaluation
  • • Atopic dermatitis
  • • Drug allergies

Parasitic Infections

  • • Tropical travel history
  • • Unexplained eosinophilia
  • • Helminth screening

Routine Monitoring

  • • Complete blood count
  • • Drug therapy monitoring
  • • Disease progression

Understanding Absolute Eosinophil Count

What is AEC?

The Absolute Eosinophil Count (AEC) is a laboratory test that measures the actual number of eosinophil white blood cells in a blood sample. Unlike the percentage of eosinophils in a differential count, the AEC provides the absolute number per unit volume of blood.

Clinical Importance

  • Diagnoses and monitors allergic conditions like asthma
  • Detects parasitic infections, especially helminths
  • Monitors drug reactions and hypersensitivity
  • Evaluates hypereosinophilic syndrome

Calculation Method

Formula

AEC = WBC Count × Eosinophil %

Required Values

  • • Total WBC count (from CBC)
  • • Eosinophil percentage (from differential)

Result Units

Usually expressed as × 10³ cells/μL or cells/μL