ANC Calculator — Absolute Neutrophil Count

Calculate absolute neutrophil count to assess infection risk and diagnose neutropenia

Calculate Absolute Neutrophil Count

×10³/μL

Normal range: 4.0-11.0 ×10³/μL

%

Mature neutrophils (40-70%)

%

Immature neutrophils (0-5%)

ANC Results

0
ANC (cells/μL)
none
Classification
No calculation
Risk Level

Formula used: ANC = WBC × (Segs% + Bands%) ÷ 100

Calculation: 0 × (0 + 0) ÷ 100 = 0 cells/μL

Normal range: 2,000-8,000 cells/μL

Clinical Interpretation

Enter values to calculate ANC

Risk Assessment: No calculation

⚠️ Medical Disclaimer: This calculator is for educational purposes only and should not replace professional medical advice. ANC values require clinical correlation and professional interpretation. Seek immediate medical attention for severe neutropenia.

Clinical Significance

Example Calculation

Patient with Mild Neutropenia

White Blood Cells: 6.0 ×10³/μL (normal range)

Neutrophil Segments: 30% (slightly low)

Neutrophil Bands: 3% (normal)

Total Neutrophil %: 30% + 3% = 33%

ANC Calculation

ANC = WBC × (Segs% + Bands%) ÷ 100

ANC = 6.0 × (30 + 3) ÷ 100

ANC = 6.0 × 33 ÷ 100

ANC = 1,980 cells/μL (Category 0 - Normal)

ANC Risk Categories

0

≥2000 cells/μL

Normal range

No increased infection risk

1

1500-2000

Borderline low

Monitor closely

2

1000-1500

Mild neutropenia

Increased infection risk

3

500-1000

Moderate neutropenia

Significant infection risk

4

<500

Severe neutropenia

Life-threatening risk

Neutrophil Types

Segments (Segs)

Mature neutrophils (40-70%)

Bands

Immature neutrophils (0-5%)

WBC Count

Total white blood cells

Left Shift: Increased bands indicate active infection or inflammation

Understanding Absolute Neutrophil Count (ANC)

What are Neutrophils?

Neutrophils are the most abundant type of white blood cells and are the first line of defense against bacterial infections. They are produced in bone marrow and circulate in the bloodstream, ready to migrate to sites of infection where they engulf and destroy bacteria through phagocytosis.

Clinical Importance of ANC

  • Assess infection risk in immunocompromised patients
  • Monitor patients undergoing chemotherapy
  • Diagnose and classify neutropenia
  • Guide antibiotic prophylaxis decisions

Causes of Neutropenia

Decreased Production

  • • Chemotherapy and radiation
  • • Bone marrow disorders
  • • Vitamin B12/folate deficiency
  • • Certain medications

Increased Destruction

  • • Autoimmune disorders
  • • Hypersplenism
  • • Viral infections (HIV, EBV)
  • • Severe bacterial infections