AST ALT Ratio Calculator
Liver function assessment using AST/ALT enzyme ratio
AST/ALT Ratio Calculation
AST/ALT Ratio Results
Medical Disclaimer
This AST/ALT ratio calculator is for educational purposes only and should not replace clinical judgment. The ratio must be interpreted alongside clinical symptoms, patient history, and additional laboratory tests. Always consult with hepatologists and gastroenterologists for proper liver disease assessment and management. Abnormal results require professional medical evaluation.
Ratio Interpretation
Important: Interpretation depends on both ratio value and whether enzymes are elevated
Normal Ranges
Normal ranges may vary between laboratories
Clinical Applications
Differentiate alcoholic vs. non-alcoholic liver disease
Screen for liver cirrhosis and fibrosis
Monitor drug-induced hepatotoxicity
Assess viral hepatitis patterns
Guide additional diagnostic testing
Understanding AST and ALT
What are AST and ALT?
AST (Aspartate Aminotransferase) and ALT (Alanine Aminotransferase) are enzymes found in liver cells. When liver cells are damaged, these enzymes leak into the bloodstream, causing their levels to rise. The ratio between these enzymes provides valuable diagnostic information.
Key Differences
- •AST: Found in liver, heart, muscles, and kidneys
- •ALT: More specific to the liver
- •ALT elevation is more specific for liver damage
- •AST can be elevated in heart attack or muscle injury
Clinical Significance
Important Considerations
Clinical Context: The ratio should always be interpreted with clinical symptoms, patient history, and additional tests.
Enzyme Levels: Both the ratio and absolute enzyme levels are important for diagnosis.
Additional Testing: May include bilirubin, albumin, PT/INR, imaging studies, and viral markers.
Follow-up: Serial measurements can help monitor disease progression and treatment response.