BED Calculator
Calculate Biologically Effective Dose (BED) and EQD2 for radiotherapy treatment planning
Calculate BED and EQD2
Select tissue type or use custom α/β ratio
Duration affects the calculation formula
Sum of all doses received
Dose received during single irradiation
Calculation Results
Formula used: BED = Total dose × (1 + (Fraction dose / α/β))
EQD₂ Formula: EQD₂ = Total dose × ((Fraction dose + α/β) / (2 + α/β))
Parameters: Total: 0 Gy, Fraction: 0 Gy, α/β: 10
Medical Disclaimer
This calculator is for educational purposes only. Results should be verified by qualified medical professionals before clinical use. Always consult with radiation oncologists for treatment planning decisions.
Clinical Interpretation
Example Calculation
Prostate Cancer Treatment
Total dose: 60 Gy
Dose per fraction: 2 Gy
Tissue type: Late reacting (α/β = 3)
Duration: Standard fractionation (< few minutes)
Calculation
BED = 60 × (1 + (2 / 3))
BED = 60 × (1 + 0.67)
BED = 100 Gy
EQD₂ = 60 × ((2 + 3) / (2 + 3)) = 60 Gy
Common α/β Ratios
Radiotherapy Guidelines
Higher α/β means more sensitive to fraction size
BED helps compare different fractionation schedules
EQD₂ standardizes dose reporting
Consider different α/β for tumor vs normal tissue
Understanding BED and EQD2
What is BED?
Biologically Effective Dose (BED) is a way to compare the biological effect of different radiotherapy fractionation schedules. It accounts for both the total dose and the dose per fraction, considering tissue radiosensitivity.
Clinical Applications
- •Compare different fractionation schemes
- •Plan hypofractionated treatments
- •Assess treatment tolerability
- •Research dose escalation studies
Formula Explanation
BED = D × (1 + d/αβ)
For standard delivery
BED = D × (1 + (g×d)/αβ)
For prolonged delivery
- D: Total dose (Gy)
- d: Dose per fraction (Gy)
- α/β: Tissue radiosensitivity ratio
- g: Dose rate factor (<1 for repair)
Note: EQD₂ normalizes treatments to 2 Gy fractions for easier comparison