Gabapentin Dosage Calculator

Calculate appropriate gabapentin dosage for various medical conditions with safety guidelines

Calculate Gabapentin Dosage

Gabapentin use in children is primarily for epilepsy treatment

Select the primary condition being treated

Optional for adult dosing reference

Gabapentin requires dose adjustment for kidney impairment

Critical Medical Warning

This calculator provides general dosing guidance only and cannot replace professional medical supervision. Gabapentin requires careful titration, monitoring for side effects, and consideration of drug interactions. Never start, stop, or change gabapentin dosing without consulting a healthcare provider.

Adult Gabapentin Dosing

300 mg
Starting Dose
Divided into 3 doses
900-1800 mg
Maintenance Dose
Target therapeutic range
3600 mg
Maximum Dose
Daily limit

Individual Dose Schedule

100 mg
Starting dose per administration
300-600 mg
Maintenance dose per administration
1200 mg
Maximum dose per administration

Dosing Schedule: Divide total daily dose into 3 equal doses, taken every 8 hours

Indication: Neuropathic Pain (Postherpetic Neuralgia, Peripheral Neuropathy)

Kidney Function: Normal (CrCl ≥60 mL/min)

Safety Assessment: Standard dosing protocol. Monitor for common side effects like drowsiness.

Typical Titration Schedule

Week 1-2: Initiation

Day 1: Start with 300mg once daily (evening)

Day 2: 300mg twice daily

Day 3+: 300mg three times daily

Monitor: Drowsiness, dizziness, peripheral edema

Week 3+: Maintenance

Increase by 300mg/day every few days as tolerated

Target effective dose based on indication

Monitor for therapeutic response and side effects

Adjust dose based on clinical response and tolerability

Common Side Effects

😴

Drowsiness

Most common side effect

Usually improves with time

💫

Dizziness

Coordination problems

Avoid driving initially

🦵

Peripheral Edema

Swelling of extremities

Monitor regularly

Drug Interactions

⚠️

Opioids: Increased CNS depression risk

⚠️

Antidepressants: Enhanced sedation

🚫

Alcohol: Avoid concurrent use

💊

Antacids: May reduce absorption

Always inform healthcare providers

Understanding Gabapentin Dosing

What is Gabapentin?

Gabapentin is an anticonvulsant medication that works by reducing abnormal electrical activity in the brain and affecting the way nerves send messages to the brain. It's structurally similar to GABA (gamma-aminobutyric acid) but works through different mechanisms.

Clinical Uses

  • FDA Approved: Epilepsy, postherpetic neuralgia
  • Off-label: Neuropathic pain, anxiety, fibromyalgia
  • Pediatric: Limited to epilepsy in children 3-12 years

Dosing Principles

Key Dosing Rules:

  • • Start low, go slow titration
  • • Kidney function determines maximum dose
  • • Divide into 2-3 daily doses (most indications)
  • • Take with food to improve tolerance

Important: Gabapentin has non-linear pharmacokinetics - higher doses are not always more effective due to saturable absorption. Individual response varies significantly, requiring careful clinical monitoring.