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HOMA-IR Calculator

Insulin Resistance Assessment Tool

Calculate HOMA-IR & QUICKI Index

⚠️

Important:

Both values must be obtained after fasting for at least 8 hours (water only).

Normal range: 70-100 mg/dL

Normal range: 2-25 mU/L (varies by lab)

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HOMA-IR Reference Ranges

Normal
Under 1.0
Healthy insulin sensitivity
⚠️
Borderline
1.0 - 2.0
Monitor and improve lifestyle
🔴
Insulin Resistance
2.0 - 2.9
Medical evaluation recommended
🚨
Significant Resistance
3.0 or higher
Immediate medical consultation

QUICKI Index Ranges

Normal
Over 0.45
Possible Resistance
0.30 - 0.45
Likely Diabetic
Under 0.30

Key Information

Requires 8+ hours fasting before blood draw

Simple alternative to invasive testing

Helps assess diabetes and prediabetes risk

Results may vary between populations

Understanding HOMA-IR and Insulin Resistance

What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a simple method to quantify insulin resistance using fasting glucose and insulin levels. It provides an estimate of insulin resistance without requiring complex testing procedures.

HOMA-IR Formula

HOMA-IR = (insulin * glucose) / 405

When glucose is in mg/dL

HOMA-IR = (insulin * glucose) / 22.5

When glucose is in mmol/L

What is QUICKI?

QUICKI (Quantitative Insulin Sensitivity Check Index) is another measure of insulin sensitivity that uses the same fasting values but with a logarithmic formula.

QUICKI = 1 / (log(insulin) + log(glucose))

Lower values indicate worse insulin sensitivity

What is Insulin Resistance?

Insulin resistance occurs when cells become less responsive to insulin, requiring higher levels to maintain normal blood glucose. This condition often precedes type 2 diabetes and is associated with metabolic syndrome.

Risk Factors

  • Obesity, especially abdominal fat
  • Sedentary lifestyle
  • Family history of diabetes
  • Age over 45 years
  • High blood pressure
  • High triglycerides or low HDL cholesterol

Improving Insulin Sensitivity

  • Regular aerobic and resistance exercise
  • Weight loss (even 5-10% helps significantly)
  • Low-glycemic diet with whole grains
  • Adequate sleep (7-9 hours per night)
  • Stress management techniques

⚠️ Important Medical Disclaimer

• This calculator is for educational purposes only and should not replace professional medical advice

• HOMA-IR values may vary between populations and laboratories

• Fasting is required for accurate results (8+ hours, water only)

• Results should be interpreted by healthcare professionals in clinical context

• Certain medications may affect insulin and glucose levels

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