Kidney Failure Risk Calculator
Calculate 5-year kidney failure risk using the KFRE equation
Calculate Kidney Failure Risk
Age in years
mL/min/1.73m² (typically 10-60 for CKD patients)
g/dL (normal: 3.5-5.0 g/dL)
mEq/L (normal: 22-26 mEq/L)
mg/dL (normal: 8.5-10.5 mg/dL)
mg/dL (normal: 2.5-4.5 mg/dL)
Risk Categories
Very High Risk
≥50% - Immediate action needed
High Risk
20-49% - Close monitoring
Moderate Risk
10-19% - Regular management
Low-Moderate Risk
5-9% - Continue monitoring
Low Risk
<5% - Routine care
About KFRE
The Kidney Failure Risk Equation (KFRE) is a validated tool that predicts the risk of kidney failure within 2 and 5 years.
Key Benefits:
Normal Lab Values
eGFR
Normal: ≥90 mL/min/1.73m²
Serum Albumin
Normal: 3.5-5.0 g/dL
Bicarbonate
Normal: 22-26 mEq/L
Calcium
Normal: 8.5-10.5 mg/dL
Phosphorus
Normal: 2.5-4.5 mg/dL
Understanding Kidney Failure Risk
What is the KFRE?
The Kidney Failure Risk Equation (KFRE) is a validated prediction model that estimates the probability of kidney failure requiring dialysis or transplantation within 2 or 5 years. It was developed using data from over 700,000 patients with chronic kidney disease.
Why is KFRE Important?
- •Helps determine urgency of nephrology referral
- •Guides timing of dialysis access creation
- •Assists in kidney transplant evaluation timing
- •Helps patients understand their prognosis
Risk Factors for Kidney Failure
Modifiable Factors
- • Blood pressure control
- • Diabetes management
- • Proteinuria reduction
- • Medication nephrotoxicity
- • Smoking cessation
Non-modifiable Factors
- • Age and sex
- • Underlying kidney disease
- • Genetic factors
- • Family history
Age & Sex
Older age and male sex are associated with higher risk of kidney failure progression.
eGFR
Lower eGFR values indicate worse kidney function and higher risk of progression.
Proteinuria (ACR)
Higher levels of protein in urine indicate kidney damage and faster progression.
Lab Values
Abnormal albumin, bicarbonate, calcium, and phosphorus levels reflect kidney dysfunction.
⚠️ Important Medical Disclaimer
This calculator is for educational purposes only and should not replace professional medical advice.
- • KFRE provides risk estimates based on population data and individual outcomes may vary
- • This tool should be used in conjunction with clinical judgment and other prognostic factors
- • Always consult with a qualified nephrologist for chronic kidney disease management
- • Risk estimates may not apply to all populations or clinical scenarios
- • Results should be interpreted within the full clinical context