Newborn Hyperbilirubinemia Assessment

Assess jaundice severity and determine treatment needs based on Bhutani nomogram

Hyperbilirubinemia Assessment

Age at time of bilirubin measurement (12-168 hours)

Total serum bilirubin concentration

Input Validation Issues:

  • Infant must be at least 12 hours old for assessment

Example Assessment

Case: 3-Day-Old Full-Term Infant

Patient: 72-hour-old full-term infant (38 weeks GA)

Bilirubin: 16.5 mg/dL

Risk Factors: None present

Assessment Result

Phototherapy Threshold: ~15.0 mg/dL

Current Level: 16.5 mg/dL (above threshold)

Recommendation: Initiate phototherapy immediately

Follow-up: Repeat bilirubin in 4-6 hours

Types of Neonatal Jaundice

Physiologic Jaundice

Starts day 2-3, resolves by day 10-14

Normal process, usually benign

Pathologic Jaundice

Starts <24h or >14 days, abnormal levels

Requires investigation and treatment

Breast Milk Jaundice

Prolonged mild jaundice in breastfed infants

Usually harmless, can last months

Treatment Modalities

💡

Phototherapy

Blue light (420-560nm) converts bilirubin to water-soluble form

🩸

Exchange Transfusion

Replace baby's blood to rapidly reduce bilirubin

💉

IVIG

For isoimmune hemolysis (Rh disease)

Clinical Risk Factors

High Risk:
  • G6PD deficiency
  • ABO/Rh incompatibility
  • Significant bruising/cephalohematoma
Moderate Risk:
  • Prematurity
  • Poor feeding/dehydration
  • Infection/sepsis
Low Risk:
  • Full-term, healthy infant
  • Good feeding/hydration
  • No risk factors

Understanding Neonatal Hyperbilirubinemia

What is Hyperbilirubinemia?

Hyperbilirubinemia is an elevated level of bilirubin in the blood, causing the yellow discoloration of skin and eyes known as jaundice. In newborns, this occurs due to immature liver function and increased breakdown of fetal hemoglobin.

Why is Monitoring Critical?

  • Prevents kernicterus (bilirubin brain damage)
  • Identifies pathological causes early
  • Guides timely treatment decisions
  • Prevents long-term neurological damage

Bhutani Nomogram

This calculator uses the Bhutani nomogram, endorsed by the American Academy of Pediatrics, to determine hour-specific bilirubin thresholds for phototherapy and exchange transfusion based on infant age and risk factors.

When to Seek Urgent Care

Immediate Medical Attention Required:

  • Jaundice appearing in first 24 hours
  • Rapidly rising bilirubin levels
  • Bilirubin above exchange transfusion threshold
  • Signs of kernicterus (lethargy, poor feeding, abnormal tone)

Critical Medical Disclaimer

This calculator is for educational and screening purposes only and should never replace professional medical evaluation. Neonatal hyperbilirubinemia can lead to serious neurological complications including kernicterus if not properly managed. Always consult with qualified pediatric healthcare professionals for assessment, diagnosis, and treatment decisions. Any infant with jaundice requires proper medical evaluation. This tool should only be used by trained healthcare professionals familiar with neonatal care guidelines.