NLR Calculator
Calculate Neutrophil-to-Lymphocyte Ratio for inflammation and stress assessment
Calculate NLR
Input Method
Normal range: 1.5-8.0 ×10³/μL
Normal range: 1.0-4.0 ×10³/μL
NLR Interpretation Guide
Clinical Significance
Inflammatory biomarker for immune system assessment
Predictor of mortality and morbidity in various conditions
Used in cardiovascular disease, cancer, and infection monitoring
Simple, cost-effective screening tool
Reference Ranges
Neutrophils (ANC)
1.5-8.0 ×10³/μL
45-75% of WBC
Lymphocytes (ALC)
1.0-4.0 ×10³/μL
20-45% of WBC
NLR (Healthy Adults)
0.78-3.53
Reference: 2017 research study
Understanding the Neutrophil-to-Lymphocyte Ratio (NLR)
What is NLR?
The Neutrophil-to-Lymphocyte Ratio (NLR) is a simple inflammatory biomarker calculated by dividing the absolute neutrophil count by the absolute lymphocyte count. It provides valuable information about immune system dysregulation, inflammation, and stress levels.
Clinical Applications
- •Cardiovascular Disease: Predicting outcomes in heart disease patients
- •Cancer: Prognosis assessment in various malignancies
- •Sepsis: Early detection and severity assessment
- •Stroke: Predicting mortality in ischemic and hemorrhagic stroke
How to Calculate NLR
NLR = ANC ÷ ALC
Where ANC = Absolute Neutrophil Count and ALC = Absolute Lymphocyte Count
Interpretation Guidelines
- Low NLR (<1): May indicate lymphocytic conditions or neutropenia
- Normal NLR (1-3): Typical range for healthy individuals
- Elevated NLR (>3): Suggests inflammation, stress, or infection
- Very High NLR (>10): Indicates significant systemic inflammation
Example Calculation
If ANC = 2,500 cells/μL and ALC = 1,500 cells/μL:
NLR = 2,500 ÷ 1,500 = 1.67 (Normal range)
Advantages
- • Cost-effective
- • Widely available
- • Easy to calculate
- • Standardized measurement
Limitations
- • Non-specific marker
- • Affected by medications
- • Age and gender variations
- • Requires clinical correlation
Important Medical Notes
- • NLR values can be affected by age, gender, and ethnicity
- • Medications such as corticosteroids can alter NLR
- • Serial monitoring is more valuable than single measurements
- • Always interpret results within the appropriate clinical context
- • Consult healthcare professionals for proper medical interpretation