Oxygenation Index Calculator

Calculate oxygenation index (OI) and assess lung function in critically ill patients

Calculate Oxygenation Index

Reference: Room air = 21%, Pure oxygen = 100%

Definition: Average pressure throughout the respiratory cycle during mechanical ventilation

Normal Range: 75-100 mmHg on room air (measured via arterial blood gas)

Oxygenation Assessment Results

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Oxygenation Index (OI)
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0
PaO₂/FiO₂ Ratio
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Formula: OI = (FiO₂ × MAP) / PaO₂

Calculation: (0.000 × 0.0) / 0.0 = 0.00

PaO₂/FiO₂ Ratio: 0.0 / 0.000 = 0

Clinical Interpretation Guide

Oxygenation Index Values:
OI < 5: Normal oxygenation
OI 5-25: Lung disease present
OI 25-40: High mortality risk
OI > 40: Consider ECMO
ARDS Classification:
P/F > 300: No ARDS
P/F 200-300: Mild ARDS
P/F 100-200: Moderate ARDS
P/F < 100: Severe ARDS

⚠️ Medical Disclaimer: This calculator is for educational purposes only. Always consult with qualified healthcare professionals for medical decisions. Clinical interpretation should consider the complete clinical picture, not just calculated values.

Example Calculation

ICU Patient Example

Patient: 65-year-old with severe pneumonia on mechanical ventilation

FiO₂: 80% (0.80)

Mean Airway Pressure: 25 cmH₂O

PaO₂: 70 mmHg

Calculation

OI = (FiO₂ × MAP) / PaO₂

OI = (0.80 × 25) / 70

OI = 20 / 70

OI = 0.29

Interpretation: Normal oxygenation (OI < 5)

Parameter Definitions

FiO₂

Fraction of inspired oxygen - percentage or decimal of oxygen in breathed air

MAP

Mean Airway Pressure - average pressure in airways throughout breathing cycle

PaO₂

Partial pressure of oxygen in arterial blood - measured via arterial blood gas

Normal Reference Values

Room Air FiO₂21%
Normal PaO₂75-100 mmHg
Normal P/F Ratio>300
Normal OI<5

Clinical Tips

Lower OI values indicate better lung function

OI is especially useful in neonatal critical care

High MAP or low PaO₂ increases OI

Trending OI values is more valuable than single measurements

Understanding the Oxygenation Index

What is the Oxygenation Index?

The Oxygenation Index (OI) is a critical care parameter that assesses the lung's ability to transfer oxygen from inhaled air into the blood. It provides a comprehensive measure of oxygenation efficiency by considering three key factors: oxygen concentration, ventilator pressure, and blood oxygen levels.

Clinical Applications

  • Assessment of acute lung injury severity
  • Decision-making for ECMO initiation
  • Monitoring treatment response in ARDS
  • Prognostic indicator in critically ill patients

Formula Explanation

OI = (FiO₂ × MAP) / PaO₂

  • Higher OI values indicate worse lung function
  • Lower PaO₂ increases OI (worse oxygenation)
  • Higher FiO₂ increases OI (more oxygen needed)
  • Higher MAP increases OI (more pressure needed)

Critical Values: OI > 40 typically indicates the need for ECMO consideration in appropriate candidates, as conventional mechanical ventilation may be insufficient.

ECMO Decision Making

Extracorporeal Membrane Oxygenation (ECMO) is considered when conventional mechanical ventilation fails to provide adequate oxygenation. The OI helps clinicians make this critical decision:

OI 25-40

Consider ECMO evaluation. Increased monitoring and aggressive management required.

OI 40-60

Strong ECMO candidacy. High mortality risk without intervention.

OI > 60

Urgent ECMO consideration. Conventional ventilation often inadequate.