Pediatric Blood Transfusion Volume Calculator

Calculate blood transfusion volume for children to achieve target hemoglobin increment

Patient Information

Pediatric weight range: 0.5-150 kg

Typical range: 55-70% for packed RBCs

Hemoglobin Information

Direct input of desired hemoglobin increase

— OR calculate increment from current and target values —

Example Calculation

5-year-old with Anemia

Patient: 5-year-old child, 20 kg

Current Hemoglobin: 6.5 g/dL

Target Hemoglobin: 9.0 g/dL

Desired Increment: 2.5 g/dL

Hematocrit of Packed RBCs: 60% (0.6 decimal)

Calculation

BTV = 20 kg × 2.5 g/dL × 3 / 0.6

BTV = 150 / 0.6

BTV = 250 mL

Volume per kg: 12.5 mL/kg (standard range)

Normal Hematocrit Values

Newborns (0-1 month)

42-65%

2nd month

33-55%

3-6 months

28-41%

6+ months

31-41%

1-5 years

31-44%

5+ years

Males: 37-48%
Females: 34-44%

Transfusion Guidelines

Maintain hemoglobin above 10 g/dL typically
Standard volume: 10-15 mL/kg
High volume (>20 mL/kg) needs monitoring
Packed RBCs hematocrit: 55-70%
Consider dividing large volumes

Safety Considerations

High Volume Transfusions:
  • Monitor for fluid overload
  • Consider dividing dose
  • Slower infusion rate
  • Cardiac monitoring may be needed
Standard Precautions:
  • Verify blood type compatibility
  • Pre-transfusion vitals
  • Monitor during infusion
  • Watch for transfusion reactions

Understanding Pediatric Blood Transfusion Volume Calculation

Why Use This Calculator?

Unlike adults where "one unit raises hemoglobin by 1 g/dL," children require precise calculations due to their varying blood volumes based on weight and age. This calculator uses the evidence-based formula from Davies et al. to ensure accurate volume calculations for pediatric patients.

Key Factors

  • Patient Weight: Determines total blood volume
  • Hematocrit: Concentration of RBCs in transfused blood
  • Hemoglobin Increment: Target increase in hemoglobin level

Formula Explanation

BTV (mL) = Weight (kg) × Increment (g/dL) × 3 / Hematocrit

  • BTV: Blood Transfusion Volume in mL
  • Weight: Patient weight in kg
  • Increment: Desired hemoglobin increase in g/dL
  • 3: Constant factor for volume calculation
  • Hematocrit: Expressed as decimal (60% = 0.6)

Source: Davies P, Robertson S, Hegde S, et al. "Calculating the required transfusion volume in children"

Critical Medical Disclaimer

This calculator provides estimates for educational purposes only and must never replace clinical judgment or established institutional protocols. Blood transfusion decisions require comprehensive patient assessment including clinical condition, laboratory values, and individual risk factors. Always verify calculations independently and consult with hematology/transfusion medicine specialists for complex cases. The actual hemoglobin response may vary based on factors not included in this formula such as ongoing blood loss, hemolysis, or dilutional effects. Healthcare providers are responsible for ensuring appropriate patient monitoring, blood product compatibility, and adherence to institutional transfusion guidelines.