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PVR Calculator

Calculate Pulmonary Vascular Resistance for assessment of pulmonary hypertension

Calculate Pulmonary Vascular Resistance

mmHg

Normal: 10-20 mmHg

mmHg

Normal: 6-12 mmHg

L/min

Normal: 4-8 L/min

PVR Results

dynes·sec·cm⁻⁵
Standard PVR Units
Wood Units
Alternative Units

Formula: PVR = 80 × (MPAP - LAP) / CO

Pressure gradient: 0.0 mmHg

Normal range: < 250 dynes·sec·cm⁻⁵

Normal range: < 3.1 Wood Units

Clinical Interpretation

Enter values to calculate PVR

Clinical Context

Example Calculation

Patient with Suspected Pulmonary Hypertension

Clinical scenario: 65-year-old patient with dyspnea on exertion

MPAP: 35 mmHg (elevated)

LAP: 8 mmHg (normal)

Cardiac Output: 4.5 L/min (low-normal)

Calculation

PVR = 80 × (35 mmHg - 8 mmHg) / 4.5 L/min

PVR = 80 × 27 / 4.5

PVR = 480 dynes·sec·cm⁻⁵

Interpretation: Moderately elevated PVR indicating pulmonary hypertension

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PVR Reference Ranges

Low PVR< 120
Normal PVR120-250
Mild elevation250-400
Moderate elevation400-800
Severe elevation> 800

All values in dynes·sec·cm⁻⁵

Factors Affecting PVR

Factors Increasing PVR

  • • Hypoxemia (low PaO₂)
  • • Acidemia (low pH)
  • • Hypercapnia (high PaCO₂)
  • • Pulmonary embolism
  • • Atelectasis
  • • Vasoconstrictor drugs

Factors Decreasing PVR

  • • Alkalemia (high pH)
  • • Hypocapnia (low PaCO₂)
  • • Exercise
  • • Vasodilator drugs
  • • Nitric oxide

Clinical Significance

💔

Elevated PVR indicates increased right heart workload

🫁

Helps diagnose pulmonary hypertension

📊

Monitors treatment response

⚕️

Guides therapeutic decisions

Understanding Pulmonary Vascular Resistance (PVR)

What is PVR?

Pulmonary Vascular Resistance (PVR) measures the resistance to blood flow through the pulmonary circulation. It helps assess the impact of pulmonary hypertension on heart function and determines the cause of any circulatory dysfunction.

Clinical Applications

  • Diagnosis of pulmonary hypertension
  • Assessment of right heart function
  • Monitoring treatment response
  • Surgical risk assessment

Formula Explanation

PVR = 80 × (MPAP - LAP) / CO

  • PVR: Pulmonary Vascular Resistance (dynes·sec·cm⁻⁵)
  • MPAP: Mean Pulmonary Arterial Pressure (mmHg)
  • LAP: Left Atrial Pressure (mmHg)
  • CO: Cardiac Output (L/min)
  • 80: Conversion factor to dynes·sec·cm⁻⁵

Important: This calculator is for educational purposes only. Always consult healthcare professionals for clinical decision-making.

Medical Disclaimer

This PVR calculator is intended for educational and informational purposes only. It should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult qualified healthcare providers before making any healthcare decisions. The accuracy of this calculator depends on the correct input of hemodynamic measurements obtained through proper clinical procedures. Clinical interpretation should always be performed by qualified medical professionals in the context of the patient's overall clinical picture.

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