URR Calculator

Calculate Urea Reduction Ratio to assess dialysis adequacy

Calculate URR

Choose Calculation Method

Urea level before dialysis session

mg/dL

Urea level after dialysis session

URR Results

Urea Reduction Ratio
Corresponding Kt/V
Kt/V = -ln(1 - URR/100)

Dialysis Adequacy Guidelines

Inadequate
URR <55%
Poor treatment effectiveness
Borderline
URR 55-64%
Consider optimization
Adequate
URR ≥65%
Target level achieved

Example Calculation

Dialysis Patient Example

Patient: 65-year-old on hemodialysis

Pre-dialysis urea: 40 mg/dL

Post-dialysis urea: 14 mg/dL

Dialysis session: 4 hours, 3 times per week

Calculation

URR = [(40 - 14) / 40] × 100%

URR = [26 / 40] × 100%

URR = 65%

Assessment: Adequate dialysis (URR ≥65%)

Corresponding Kt/V: -ln(1 - 0.65) ≈ 1.05

Medical Disclaimer

This calculator is for educational purposes only and should not replace professional medical assessment. URR monitoring and dialysis adequacy evaluation require clinical expertise and should always be supervised by qualified nephrologists and dialysis professionals. Inadequate dialysis can lead to serious health complications and increased mortality risk.

Quick Reference

Target Values

URR Target: ≥65%
Kt/V Target: ≥1.2
Monitoring: Monthly

URR Formula

[(Pre-urea - Post-urea) / Pre-urea] × 100%

Improving URR

Increase dialysis session time

Optimize blood flow rate through dialyzer

Address vascular access problems

Ensure proper dialyzer function

Clinical Importance

⚠️

URR <65% increases mortality risk

Regular monitoring improves outcomes

ℹ️

Simple assessment of dialysis quality

📊

Correlates with patient survival

Understanding URR - Urea Reduction Ratio

What is URR?

The Urea Reduction Ratio (URR) is a simple measure of dialysis adequacy that quantifies the effectiveness of a dialysis treatment. It represents the percentage reduction in blood urea nitrogen (BUN) from the beginning to the end of a dialysis session.

Why is URR Important?

  • Simple assessment of dialysis effectiveness
  • Correlates with patient survival outcomes
  • Easy to calculate and monitor regularly
  • Helps optimize dialysis prescriptions

URR vs. Kt/V

URR Advantages

  • • Simple calculation
  • • No body weight needed
  • • Easy to understand
  • • Quick assessment

Kt/V Advantages

  • • More comprehensive measure
  • • Accounts for body size
  • • Better for treatment planning
  • • International standard

Clinical Guidelines and Standards

The URR target of ≥65% is based on clinical studies showing improved patient outcomes. This corresponds to a Kt/V of approximately 1.2. However, many dialysis units aim for higher targets to ensure adequate treatment despite variations in blood sampling and measurement.

Monitoring Schedule

  • • Monthly URR assessment for all patients
  • • More frequent monitoring for unstable patients
  • • Assessment after any dialysis prescription changes
  • • Quality assurance for dialysis adequacy programs