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Creatinine Clearance Calculator

Calculate creatinine clearance using the Cockcroft-Gault equation to assess kidney function

Calculate Creatinine Clearance

Age in years (1-120)

Sex affects the calculation coefficient

Current body weight

Height for BMI and weight adjustment calculation

Normal range: 0.7-1.3 mg/dL (62-115 µmol/L)

Creatinine Clearance Results

0.0
mL/min
BMI
0.0
Underweight
Weight Used
0.0 kg
Actual
Sex Coefficient
1.0
Male

Cockcroft-Gault Formula: CrCl = (140 - age) × weight × sex / (72 × sCr)

Calculation: (140) × 0.0 × 1 / (72 × 0.00)

Medical Disclaimer

This calculator provides estimates based on the Cockcroft-Gault equation and should not replace professional medical advice. Kidney function assessment requires clinical interpretation alongside medical history and other laboratory findings. Always consult healthcare professionals for medical decisions and drug dosing adjustments.

Example Calculation

Case: 67-year-old Male Patient

Age: 67 years

Weight: 92 kg (BMI 30.74 - Obese)

Height: 173 cm

Serum Creatinine: 1.4 mg/dL

Sex: Male

Step-by-Step Calculation

1. Calculate IBW: 50 + 0.9 × (173 - 152) = 68.9 kg

2. Calculate ABW: 68.9 + 0.4 × (92 - 68.9) = 78.14 kg

3. Apply Cockcroft-Gault: (140 - 67) × 78.14 × 1 / (72 × 1.4)

Result: 56.6 mL/min

Interpretation: Moderately decreased kidney function (CKD Stage 3b)

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CKD Stages Reference

Stage 1: ≥90 mL/min
Normal (with kidney damage)
Stage 2: 60-89 mL/min
Mildly decreased
Stage 3a: 45-59 mL/min
Moderately decreased
Stage 3b: 30-44 mL/min
Moderately decreased
Stage 4: 15-29 mL/min
Severely decreased
Stage 5: <15 mL/min
Kidney failure

Weight Adjustment

Underweight (BMI <18.5): Use actual body weight
Normal weight (BMI 18.5-25): Use ideal body weight
Overweight/Obese (BMI ≥25): Use adjusted body weight with 40% correction factor

Understanding Creatinine Clearance

What is Creatinine Clearance?

Creatinine clearance (CrCl) is a measure of kidney function that estimates the glomerular filtration rate (GFR). It represents the volume of blood plasma cleared of creatinine per unit time, providing insight into how well the kidneys are filtering waste products.

Clinical Applications

  • Assessing kidney function in chronic kidney disease
  • Medication dosing adjustments for renally cleared drugs
  • Monitoring progression of kidney disease
  • Pre-operative assessment for surgery

Cockcroft-Gault Equation

CrCl = (140 - age) × weight × sex / (72 × sCr)

  • CrCl: Creatinine clearance (mL/min)
  • Age: Patient age in years
  • Weight: Body weight (adjusted for BMI)
  • Sex: 1 for males, 0.85 for females
  • sCr: Serum creatinine (mg/dL)

Note: This calculator automatically adjusts weight based on BMI using established clinical guidelines to improve accuracy in underweight, normal weight, and obese patients.

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