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GFR Calculator

Calculate estimated Glomerular Filtration Rate for kidney function assessment

Calculate eGFR

Valid for adults 18+ years

Normal: 0.7-1.3 mg/dL (62-115 μmol/L)

CKD Stages by eGFR

Stage 1
≥90 mL/min/1.73m²
Normal or High
Stage 2
60-89 mL/min/1.73m²
Mildly Decreased
Stage 3a
45-59 mL/min/1.73m²
Mildly to Moderately Decreased
Stage 3b
30-44 mL/min/1.73m²
Moderately to Severely Decreased
Stage 4
15-29 mL/min/1.73m²
Severely Decreased
Stage 5
<15 mL/min/1.73m²
Kidney Failure
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Which Method to Use?

Creatinine Only

Standard method, widely available test

Cystatin C Only

Better for patients with unusual muscle mass

Both Combined

Most accurate, recommended when both available

Normal Lab Values

Serum Creatinine

Male: 0.9-1.3 mg/dL

Female: 0.7-1.1 mg/dL

Serum Cystatin C

Adult: 0.5-1.2 mg/L

Normal eGFR

Adults: 90-120 mL/min/1.73m²

Important Notes

eGFR decreases naturally with age
Values may vary between laboratories
Cystatin C is less affected by muscle mass
Combined method provides best accuracy

Understanding eGFR (Estimated Glomerular Filtration Rate)

What is eGFR?

eGFR measures how well your kidneys filter blood. It estimates the volume of blood filtered by the glomeruli (tiny kidney filters) per minute, standardized to 1.73 m² body surface area. This standardization allows comparison between people of different sizes.

Why is eGFR Important?

  • Early detection of kidney disease
  • Monitoring progression of chronic kidney disease
  • Guiding treatment decisions
  • Determining need for specialist referral

Calculation Methods

CKD-EPI (2009)

Most widely used, based on creatinine

CKD-EPI Cystatin C

Independent of muscle mass

CKD-EPI Combined

Uses both markers, most accurate

MDRD

Alternative method, less accurate

Factors Increasing Creatinine

  • • High muscle mass
  • • High protein diet
  • • Creatine supplements
  • • Certain medications
  • • Dehydration

Factors Decreasing Creatinine

  • • Low muscle mass
  • • Advanced age
  • • Vegetarian diet
  • • Malnutrition
  • • Pregnancy

Advantages of Cystatin C

  • • Not affected by muscle mass
  • • More stable production
  • • Better in elderly patients
  • • Useful in special populations

⚠️ Important Medical Disclaimer

This calculator is for educational purposes only and should not replace professional medical advice.

  • • Always consult with a qualified physician for kidney function evaluation
  • • eGFR should be interpreted within the full clinical context
  • • Consider other kidney function tests and clinical findings
  • • Regular monitoring may be needed for chronic kidney disease
  • • Different laboratories may have slightly different reference ranges
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