SAAG Calculator
Calculate Serum-Ascites Albumin Gradient for ascites evaluation and portal hypertension diagnosis
Calculate SAAG
Normal range: 3.5-5.0 g/dL (35-50 g/L)
Obtained via paracentesis (abdominal tap)
SAAG Results
Formula: SAAG = Serum Albumin - Ascitic Fluid Albumin
Critical threshold: 1.1 g/dL (11 g/L)
Clinical Significance
Example Calculation
Portal Hypertension Case
Patient: 55-year-old with cirrhosis and ascites
Serum albumin: 4.23 g/dL
Ascitic fluid albumin: 3.54 g/dL
Calculation
SAAG = 4.23 - 3.54 = 0.69 g/dL
Result: 0.69 g/dL (portal hypertension)
Interpretation: Consistent with hepatic ascites
SAAG Interpretation Guide
≥1.1 g/dL (≥11 g/L)
Portal hypertension
97% accuracy, transudate
<1.1 g/dL (<11 g/L)
Non-portal etiology
Peritoneal origin, exudate
Quick Reference
Normal serum albumin: 3.5-5.0 g/dL
Ascitic fluid obtained via paracentesis
Simultaneous measurements required
More reliable than total protein
Understanding SAAG (Serum-Ascites Albumin Gradient)
What is SAAG?
The serum-ascites albumin gradient (SAAG) represents the albumin concentration difference between blood serum and ascitic fluid. It helps physicians differentiate the mechanisms of abnormal fluid accumulation, particularly portal hypertension.
Clinical Importance
- •97% accuracy in diagnosing portal hypertension
- •More reliable than ascitic fluid total protein
- •Guides appropriate treatment strategies
- •Helps identify underlying pathophysiology
What is Ascites?
Ascites is the buildup of more than 25 mL of fluid in the peritoneal cavity. It can arise through various mechanisms with different underlying causes.
Fluid Classification
Transudate (SAAG ≥1.1)
Results from elevated hydrostatic pressure or decreased oncotic pressure. Associated with portal hypertension.
Exudate (SAAG <1.1)
Results from inflammation or infection of peritoneal surfaces. Associated with peritoneal disorders.
Important Medical Disclaimer
This SAAG calculator is for educational purposes only and should not replace professional medical judgment. The interpretation of SAAG results must be considered in the context of the patient's clinical presentation.
Always consult with qualified healthcare professionals for:
- Clinical interpretation of results
- Diagnosis and treatment decisions
- Management of ascites and underlying conditions
- Appropriate follow-up care
Emergency medical attention should be sought immediately if a patient shows signs of spontaneous bacterial peritonitis, hepatic encephalopathy, or other serious complications.